Children |
| 1. Victoria Alberta Elisabeth Mathilde Marie Hesse-Darmstadt, Marchioness of Milford Haven, b. 5 April 1863, Windsor Castle, Windsor, Berkshire, England |
| 2. Elisabeth Alexandra Louise Alice Hesse-Darmstadt, Grand Duchess Elizabeth Ferdinovna of Russia, Nun, Saint, b. 1 Nov 1864, Hesse, Germany |
| 3. Irene Louise Marie Anne Hesse-Darmstadt, Princess Henry of Prussia, b. 11 July 1866, Darmstadt, Hesse, Germany |
| 4. Ernst Ludwig Karl Albrecht Wilhelm Hesse-Darmstadt, Grand Duke Hesse & By Rhine, b. 25 November 1868, Darmstadt, Hesse, Germany |
| 5. Friedrich Wilhelm August Victor Leopold Ludwig Hesse-Darmstadt, Prince, b. 07 Oct 1870, New Palace, Darmstadt, Hesse, Germany |
+ | 6. Alix Victoria Helena Luise Beatrice Hesse-Darmstadt, Empress Alexandra of Russia, b. 6 June 1872, Darmstadt, German Empire |
| 7. Marie Victoria Feodore Leopoldine Hesse-Darmstadt, Princess May, b. 24 May 1874, Darmstadt, Hesse, Germany |
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