1531-1586
| George (5th Lord Seton) Seton | |
| B: | 1531 |
| Tranent, East Lothian, Scotland | |
| D: | 8 Jan 1586 |
| Seton, East Lothian, Scotland | |
1534-1604
| Isabel Hamilton | |
| B: | c1534 |
| Sanquhar, Dumfries-shire, Scotland | |
| D: | 13 Nov 1604 |
| Renfrew, Renfrewshire, Scotland | |
1508-1549
| George (4Th Lord Seton) Seton | |
| B: | 1508 |
| Seton, East Lothian, Scotland | |
| D: | 17 Jul 1549 |
| Culrosse, Fife, Scotland | |
1510-1549
| Elizabeth Hay | |
| B: | 1510 |
| Culross, Perthshire, Scotland | |
| D: | 1549 |
| Culross, Fife, Scotland | |
1481-1513
| George (3rd Lord Seton) Seton | |
| B: | 1481 |
| Thirlstone, Berwichshire, Scotland | |
| D: | 9 Sep 1513 |
| killed at the Battle of Flodden, Northumberland, England | |
1485-1558
| Janet Hepburn | |
| B: | 1485 |
| Bothwell, Lanarkshire, Scotland | |
| D: | 10 May 1558 |
| East Lothian, Scotland | |
1433-1481
| Margaret Campbell | |
| B: | 1433 |
| Scotland | |
| D: | Feb 1481 |
| Scotland | |
1449-1508
| George (2nd Lord Seton) Seton | |
| B: | 1449 |
| East Lothian, Scotland | |
| D: | 6 Apr 1508 |
| Prestonpans, East Lothian, Scotland | |