1424-1471
| Margaret Seton | |
| B: | 1424 |
| Seton, East Lothian, Scotland | |
| D: | 1471 |
| Scotland | |
1457-1510
| Martha Seton | |
| B: | 1457 |
| Scotland | |
| D: | 1510 |
| Lauder, Berwickshire, Scotland | |
1475-1510
| Martha DeSeton Lady Thirlestane | |
| B: | 1475 |
| Prestonpans, East Lothian, Scotland | |
| D: | 1510 |
| Haddington, East Lothian, Scotland | |
1479-
| Robert Seton | |
| B: | 1479 |
| East Lothian, Scotland | |
1480-1535
| Margaret Seton | |
| B: | 1480 |
| Scotland | |
| D: | 1535 |
| Scotland | |
1482-
| Katherine Seton | |
| B: | 1482 |
| East Lothian, Scotland | |
1449-1508
| George (2nd Lord Seton) Seton | |
| B: | 1449 |
| East Lothian, Scotland | |
| D: | 6 Apr 1508 |
| Prestonpans, East Lothian, Scotland | |
1456-1481
| Lady Marian Margaret Campbell | |
| B: | 2 Feb 1456 |
| Inveraray, Argyll, Scotland | |
| M: | 14 Sep 1469 |
| Donegal, Ireland | |
| D: | 1481 |
| Seton Manor, East Lothian, Scotland | |
1481-1513
| George (3rd Lord Seton) Seton | |
| B: | 1481 |
| Thirlstone, Berwichshire, Scotland | |
| D: | 9 Sep 1513 |
| killed at the Battle of Flodden, Northumberland, England | |
1485-1558
| Janet Hepburn | |
| B: | 1485 |
| Bothwell, Lanarkshire, Scotland | |
| D: | 10 May 1558 |
| East Lothian, Scotland | |
1433-1481
| Margaret Campbell | |
| B: | 1433 |
| Scotland | |
| D: | Feb 1481 |
| Scotland | |
1450-1523
| Alexander Seton | |
| B: | 1450 |
| Haddington, East Lothian, Scotland | |
| D: | 21 Jan 1523 |
| Perth, Perthshire, Scotland | |
1462-1491
| John Seton | |
| B: | 1462 |
| Byres, East Lothian, Scotland | |
| D: | 1491 |
1428-1476
| John, (4th Earl of Seton) Seton | |
| B: | 1428 |
| Seton, East Lothian, Scotland | |
| D: | 19 Jul 1476 |
| Seton, East Lothian, Scotland | |
1430-1496
| Lady Christian DeLindsay of Seton | |
| B: | 1430 |
| Haddington, East Lothian, Scotland | |
| M: | 20 June 1449 |
| East Lothian, Scotland | |
| D: | 11 Mar 1496 |
| Glencairn, Dumfries-shire, Scotland | |
1440-
| Christian Seton | |
| B: | 1440 |
| Seton, East Lothian, Scotland | |
|
1406-1461
| Margaret Stewart | |
| B: | January 1406 |
| Seton, East Lothian, Scotland | |
| D: | 8 January 1461 |
| Seton, East Lothian, Scotland | |
1404-1478
| George Seton | |
| B: | 1404 |
| Seton, East Lothian, Scotland | |
| M: | 18 January 1437 |
| Buchan, Aberdeenshire, Scotland | |
| D: | 14 July 1478 |
| Edinburgh, Midlothian, Scotland | |