| # | Children | Name | Born | Died | Father | Mother |
|---|
| 1 | | | b. 19 Nov 1822 | d. 5 Oct 1841 | Leopold II Grand Duke of Tuscany | Maria Anna Caroline Princess of Saxony |
| 2 | | | b. 1 Apr 1825 | d. 26 Apr 1864 | Leopold II Grand Duke of Tuscany | Maria Anna Caroline Princess of Saxony |
| 3 | | | b. 9 Jan 1827 | d. 18 May 1834 | Leopold II Grand Duke of Tuscany | Maria Anna Caroline Princess of Saxony |
| 4 | | | b. 21 May 1834 | d. 14 Jul 1901 | Leopold II Grand Duke of Tuscany | Maria Antonia, Princess of the Two Sicilies |
| 5 | | | b. 10 Jun 1835 | d. 17 Jan 1908 | Leopold II Grand Duke of Tuscany | Maria Antonia, Princess of the Two Sicilies |
| 6 | | | b. 29 Jun 1836 | d. 5 Aug 1838 | Leopold II Grand Duke of Tuscany | Maria Antonia, Princess of the Two Sicilies |
| 7 | | | b. 5 Feb 1838 | d. 1 Sep 1849 | Leopold II Grand Duke of Tuscany | Maria Antonia, Princess of the Two Sicilies |
| 8 | | | b. 30 Apr 1839 | d. 18 Jan 1892 | Leopold II Grand Duke of Tuscany | Maria Antonia, Princess of the Two Sicilies |
| 9 | | | b. 9 Jun 1840 | d. 13 Aug 1841 | Leopold II Grand Duke of Tuscany | Maria Antonia, Princess of the Two Sicilies |
| 10 | | | b. 1 May 1842 | d. 14 Aug 1844 | Leopold II Grand Duke of Tuscany | Maria Antonia, Princess of the Two Sicilies |
| 11 | | | b. 31 Oct 1845 | d. 27 Aug 1917 | Leopold II Grand Duke of Tuscany | Maria Antonia, Princess of the Two Sicilies |
| 12 | | | b. 4 Aug 1847 | d. 12 Oct 1915 | Leopold II Grand Duke of Tuscany | Maria Antonia, Princess of the Two Sicilies |
| 13 | | | b. 25 Nov 1852 | d. 10 Jul 1890 | Leopold II Grand Duke of Tuscany | Maria Antonia, Princess of the Two Sicilies |
English
1797 - 1870 (72 years)