3. | Isabel Hamilton was born in c1534 in Sanquhar, Dumfries-shire, Scotland; died on 13 Nov 1604 in Renfrew, Renfrewshire, Scotland. Children:
- George Seton was born in 1550 in East Lothian, Scotland; died in Mar 1562 in Scotland.
- 1. Grizel Semple was born in 1551 in Blair, Ayrshire, Scotland; died on 8 Feb 1572.
- Margaret Hamilton was born in 1551; died on 10 Feb 1616.
- Robert Seton Winton was born in 1553 in 1684806, East Lothian, Scotland; died on 22 Mar 1602 in 1684806, East Lothian, Scotland.
- Alexander (1st Earl of Dunfermline) Seton was born in 1555 in Seton, East Lothian, Scotland; died on 16 Jun 1622 in Killed at the Battle of Pinkie, Edinburgh, Mid Lothian, Scotland.
- Margaret Seton was born in 1556 in 1684806, East Lothian, Scotland; died on 10 Feb 1616 in Scotland.
- James Seton was born in 1560.
- William Seton was born in 1562 in Dunbar Castle, East Lothian, Scotland; died in Jul 1635 in Kyllismore, Scotland.
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